目录号 | 产品详情 | 靶点 | |
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T82764 | |||
Cd1a是从非洲蜘蛛Ceratogyrus darlingi中提取的β-毒素,具有调节钙离子通道的功能。它能够抑制人类的钙离子通道(Cav2.2)(IC50 2.6 μM)以及小鼠的钠离子通道(Nav1.7),有望用于开发治疗外周疼痛的药物。 | |||
TN4108 | Antifection | ||
The binding affinities of ganoderic acid DM and ganoderic acid Z (ÎGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug oseltamivir (-23.62 kcal mol-1);Ganoderic acid DM is a potential source of anti-influenza ingredient, with novel binding pattern and advantage over oseltamivir, it has steric hindrance on the 150 cavity of N1 protein, and exerts activities across the H274Y and N294S mutations, is the attractive candidates of novel neuraminidase (NA) inhibitors.Ganoderic acid zeta has cytotoxicity in vitro against Meth-A and LLC cell lines. | |||
T37608 | |||
Riluzole-13C,15N2 is intended for use as an internal standard for the quantification of riluzole by GC- or LC-MS. Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis. | |||
TP1972 | |||
Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM). Inhibits fast inactivation on all channels. Increases | |||
TP1513 | |||
Egg-laying hormone (ELH) is a neuropeptide synthesized by the bag cell neurons, Egg-laying hormone (ELH) induces egg laying and its correlated behavior in Aplysia californica. Egg-laying hormone (ELH) has been purified to homogeneity and Egg-laying hormon | |||
T69652 | |||
Relutrigine (PRAX-562) 是一种口服活性的持久性钠通道 (sodium channel) 抑制剂,能够有效优先抑制由 ATX-II (Nav 1.5 激活剂) 或 SCN8A 突变 N1768D 引起的持续性 INa,其 IC50 值分别为 141 nM 和 75 nM。该化合物通过使用依赖性阻断方式,降低神经元的内在兴奋性,显示出明显的抗惊厥活性。 | |||
T36998 | |||
7β,27-dihydroxy Cholesterol is an oxysterol and agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and RORγt. [1] It activates RORγ- or RORγt-dependent signaling with EC50 values of 691 and 1,045 nM, respectively, in reporter assays using HEK293T cells expressing the recombinant human receptors. 7β,27-dihydroxy Cholesterol is selective for RORγ and RORγt over a panel of eight additional nuclear receptors at 30 µM. It increases IL-17A production in Th17-polarized isolated human na ve CD4+ T cells when used at a concentration of 300 nM. 7β,27-dihydroxy Cholesterol (60 mg/kg) increases IL-17A production in isolated mouse γδ T cells stimulated with 12-myristate 13-acetate and ionomycin . | |||
T19580 | Thrombin | ||
Thrombin (MW 37kDa) 是一种 Na+激活的胰蛋白酶样别构丝氨酸蛋白酶。它能够利用凝血酶识别序列对融合蛋白进行位点特异性切割,并可用于消化 GST 标记的蛋白。 | |||
TN1875 | BCL Caspase p53 | ||
Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can suppress ventricular arrhythmias induced by myocardial ischaemia reperfusion, through inhibiti | |||
T13177 | |||
Tocainide hydrochloride 是一种sodium channel 阻滞剂,它阻断神经膜中产生疼痛的病灶中的钠通道。Tocainide hydrochloride 是利多卡因 (lignocaine) 的一种伯胺类似物,可有效抑制各种情况下的室性心律失常。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-06067 | Influenza A H1N1 (A/Brisbane/02/2018) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Brisbane/02/2018) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.3 kDa.
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TMPY-06066 | Influenza A H3N2 (A/Kansas/14/2017) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Kansas/14/2017) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is A0A2L2FIU4.
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TMPY-02344 | Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50 kDa and the accession number is C3W5S3.
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TMPY-05204 | Influenza A H1N1 (A/Michigan/45/2015) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Michigan/45/2015) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa.
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TMPY-03845 | Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His) | H7N9 | HEK293 Cells | ||
Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa.
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TMPY-02336 | Influenza A H3N2 (A/Babol/36/2005) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Babol/36/2005) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is C0LU95.
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TMPY-04337 | Influenza A H1N1 (A/Puerto Rico/8/1934) Neuraminidase/NA Protein | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Puerto Rico/8/1934) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.1 kDa and the accession number is P03468.2.
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TMPY-05205 | Influenza A H3N2 (A/Hong Kong/4801/2014) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Hong Kong/4801/2014) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.5 kDa.
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TMPY-00602 | Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is Q75VQ4.1.
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TMPY-06801 | Influenza A H1N1 (A/Wisconsin/67/2022) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Wisconsin/67/2022) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.34 kDa.
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TMPY-06489 | Influenza A H3N2 (A/Darwin/9/2021) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Darwin/9/2021) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.88 kDa.
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TMPY-06891 | Influenza A H1N1 (A/Sydney/5/2021) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Sydney/5/2021) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.33 kDa.
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TMPY-06470 | Influenza A H3N2 (A/Hong Kong/2671/2019) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Hong Kong/2671/2019) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.08 kDa.
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TMPY-06852 | Influenza A H1N1 (A/California/07/2009) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/California/07/2009) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.28 kDa.
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TMPY-06446 | Influenza A H3N2 (A/England/42/1972) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/England/42/1972) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.78 kDa.
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TMPY-06799 | Influenza A H1N1 (A/Victoria/4897/2022) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Victoria/4897/2022) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.39 kDa.
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TMPY-05926 | Influenza A H1N1 (A/AA/Marton/1943) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/AA/Marton/1943) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.1 kDa and the accession number is A4GBW9.
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TMPY-06163 | Influenza A H3N2 (A/Cambodia/e0826360/2020) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Cambodia/e0826360/2020) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.7 kDa.
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TMPY-06889 | Influenza A H3N2 (A/Hong Kong/01/1968) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Hong Kong/01/1968) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.82 kDa.
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TMPY-06517 | Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.64 kDa and the accession number is AKM14549.
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TMPY-00373 | Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein (His) | H7N7 | HEK293 Cells | ||
Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa and the accession number is Q6VGI7.
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TMPY-06182 | Influenza A H3N2 (A/Singapore/INFIMH-16-0019/2016) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Singapore/INFIMH-16-0019/2016) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.7 kDa.
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TMPY-00019 | Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase/NA Protein (His) | H10N8 | Baculovirus Insect Cells | ||
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is I6PU08.
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TMPY-06162 | Influenza A H1N1 (A/Wisconsin/588/2019)/(A/Victoria/2570/2019) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Wisconsin/588/2019)/(A/Victoria/2570/2019) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.3 kDa.
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TMPY-00143 | Influenza A H5N1 (A/Thailand/1(KAN-1)/2004) Neuraminidase/NA Protein (His), Biotinylated | H5N1 | HEK293 Cells | ||
Influenza A H5N1 (A/Thailand/1(KAN-1)/2004) Neuraminidase/NA Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa.
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TMPY-02528 | Influenza A H9N2 Neuraminidase/NA Protein | H9N2 | HEK293 Cells | ||
Influenza A H9N2 Neuraminidase/NA Protein is expressed in HEK293 mammalian cells.
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TMPY-02448 | Influenza A H3N2 Neuraminidase/NA Protein | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-04185 | Influenza A H4N6 (A/mallard/Ohio/657/2002) Neuraminidase/NA Protein (His) | H4N6 | Baculovirus Insect Cells | ||
Influenza A H4N6 (A/mallard/Ohio/657/2002) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A4JYU4.
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TMPY-02339 | Influenza A H3N2 Neuraminidase/NA Protein (R292K) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein (R292K) is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-02338 | Influenza A H3N2 Neuraminidase/NA Protein (N294S) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein (N294S) is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-02152 | Influenza A H5N1 Neuraminidase/NA Protein (H255Y) | H5N1 | HEK293 Cells | ||
Influenza A H5N1 Neuraminidase/NA Protein (H255Y) is expressed in HEK293 mammalian cells. The predicted molecular weight is 49.2 kDa and the accession number is A7Y9K2.
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TMPY-04338 | Influenza A H3N2 Neuraminidase/NA Protein (H274Y) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein (H274Y) is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-04048 | Influenza A H1N1 Neuraminidase/NA Protein (N295S) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 Neuraminidase/NA Protein (N295S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 52 kDa and the accession number is C3W5S3.
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TMPY-02337 | Influenza A H3N2 Neuraminidase/NA Protein (E119V) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein (E119V) is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-02151 | Influenza A H1N1 Neuraminidase/NA Protein (H275Y) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 Neuraminidase/NA Protein (H275Y) is expressed in HEK293 mammalian cells. The predicted molecular weight is 47.8 kDa and the accession number is C3W5S3.
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TMPY-04885 | Influenza B (B/PHUKET/3073/2013) Neuraminidase/NA Protein (His) | Influenza B | Baculovirus Insect Cells | ||
Influenza B (B/PHUKET/3073/2013) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.5 kDa.
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TMPY-03843 | Influenza A H7N9 (A/Shanghai/1/2013) Neuraminidase/NA Protein | H7N9 | HEK293 Cells | ||
Influenza A H7N9 (A/Shanghai/1/2013) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells.
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TMPY-04849 | Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 52.2 kDa and the accession number is Q75VQ4.1.
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TMPY-05925 | Influenza A H1N1 (A/Henry/1936) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Henry/1936) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is A4GCI9.
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TMPY-05938 | Influenza A H3N2 (A/Albany/18/1968) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Albany/18/1968) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is A4JZ31.
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TMPY-04532 | Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein | H7N9 | HEK293 Cells | ||
Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells.
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TMPY-00958 | Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA (Fc) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 76 kDa and the accession number is C3W5S3.
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TMPY-05930 | Influenza A H1N1 (A/Auckland/6/1996) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Auckland/6/1996) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.5 kDa and the accession number is A5JVE2.
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TMPY-05929 | Influenza A H1N1 (A/Beijing/262/1995) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Beijing/262/1995) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is B4UPG0.
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TMPY-05927 | Influenza A H1N1 (A/Baylor/11515/1982) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Baylor/11515/1982) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is Q1WP17.
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TMPY-05933 | Influenza A H1N1 (A/Arizona/13/2008) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Arizona/13/2008) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is B9W3K0.
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TMPY-05757 | Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His), Biotinylated | H7N9 | HEK293 Cells | ||
Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa.
|
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TMPY-05942 | Influenza A H3N2 (A/Hong Kong/CUHK19579/1998) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Hong Kong/CUHK19579/1998) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is B5ALX7.
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TMPY-04850 | Influenza A H1N1 (A/USSR/90/1977) Neuraminidase/NA Protein | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/USSR/90/1977) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 51.9 kDa and the accession number is P03469.2.
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TMPY-05931 | Influenza A H1N1 (A/Auckland/606/2001) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Auckland/606/2001) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A6M7B6.
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